温敏性荧光纳米材料的合成  

Synthesis of Thermosensitive Fluorescence Nanoparticles

作　　者：仲慧[1] 李康[1] 徐继明[1] 张莉莉[1] 张维光[1] 赵宜江[1] 张贵方[1] 

机构地区：[1]江苏省低维材料化学重点实验室,淮阴师范学院化学系

出　　处：《化学通报》2007年第7期541-546,共6页Chemistry

基　　金：江苏省教育厅自然科学基金(04KJB150016);江苏省自然科学基金(BK2006061);江苏省低维材料化学重点实验室开放课题(JSKC06029)资助

摘　　要：合成了以荧光材料罗丹明B/SiO2为核,交联聚N-异丙基丙烯酰胺(PNIPAM)为壳的具有核/壳结构的纳米颗粒。用氢氟酸除去二氧化硅模板核后,形成了核壳结构的温敏荧光微球。28～36℃范围内的温敏性实验表明,该粒子的低临界溶解温度(LCST)为33℃,具有温敏性,用SEM、TEM、XRD、FT-IR等手段对温敏荧光微球的组成和结构进行了表征和分析,探讨了磁性温敏纳米颗粒的制备机理。Novel thermosensitive fluorescence nanoparticles are synthesized. Firstly, the core-shell composite microparticles were synthesized by precipitation polymerization with Rhodamine B entrapped SiO2 as core and cross-linked poly（N-isopropylacrylamide） （PNIPAM） as shell. Then, the SiO2 core was etched by hydrofluoric acid at certain condition and the pre-trapped Rhodamine B molecules remained within the inner cavity. It has been also shown that the modified Rhodamine B are featured by lower critical solution temperature （LCST） while the temperature varies from 28℃ to 36℃ . The composite thermosensitive fluorescence particles were characterized by XRD, SEM, TEM and FT-IR.

关 键 词：温敏 核壳 纳米颗粒 罗丹明B 

分 类 号：TB383.1[一般工业技术—材料科学与工程]