利用模式生物线虫评价精对苯二甲酸废水的毒性  

Toxicity evaluation of purified terephthalic acid wastewater by using model Caenorhabditis elegans

作　　者：王晓祎[1] 王大勇[2] 于红霞[1] 王晓蓉[1] 张徐祥[1] 程树培[1] 

机构地区：[1]南京大学环境学院污染控制与资源化研究国家重点实验室,南京210093 [2]东南大学基础医学院发育与疾病相关基因教育部重点实验室,南京210009

出　　处：《应用生态学报》2007年第7期1669-1672,共4页Chinese Journal of Applied Ecology

基　　金：国家自然科学基金重点资助项目(20237010).

摘　　要：应用模式生物秀丽隐杆线虫,通过生命周期、半数致死天数、生殖速度、产卵数、头部摆动频率和身体弯曲次数等指标对精对苯二甲酸(PTA)废水毒性进行了研究.结果表明,与对照组相比,660mg·L-1PTA废水暴露下的线虫生命周期有一定的延长,产卵时间延迟,头部摆动频率降低,身体弯曲次数减少(P<0.05),且PTA废水对线虫生殖能力的影响极显著(P<0.01),暴露于废水中的线虫产卵数大约只有正常产卵数的1/4.最敏感效应指标——产卵数,有望成为该类废水毒性预警预报的潜在生物标志物.By using model Caenorhabditis elegans, the toxicity of purified terephthalic acid （PTA） wastewater was evaluated through a battery of biotest, including life span, days of 50% lethal, generation time, brood size, head thrashes, and body bends. The results revealed that compared with control, the life span and generation time of C. elegans exposed to 660 mg PTA· L^-1 were delayed to some degree, and its head thrashes and body bends were inhibited. The procreation function of C. elegans exposed to PTA wastewater was greatly affected, with the brood size being as low as 25% of the normal one. The most sensitive indicator, indicator in evaluating PTA wastewater toxicity. brood size of C. elegans, might be a potential

关 键 词：秀丽隐杆线虫 PTA废水 毒性评价 

分 类 号：X703[环境科学与工程—环境工程]