胰岛素泵和多次皮下注射治疗糖尿病的比较  

Comparison of insulin pump and continuous subcutaneous injection in the treatment of diabetes

作　　者：杨志霞[1] 郭莹辉[1] 杨永生[2] 刘慧琴[1] 高月华[1] 

机构地区：[1]廊坊市人民医院内分泌科,065000 [2]廊坊市中医院外科,065000

出　　处：《国际内分泌代谢杂志》2007年第4期283-285,共3页International Journal of Endocrinology and Metabolism

摘　　要：目的在新住院的糖尿病患者中,比较不同类型的胰岛类似物以及不同的注射方式在血糖控制、治疗费用和依从性的差异。方法选择100例糖尿病患者,分为2组,每组各50例。其中一组应用长效胰岛素类似物联合速效胰岛素类似物多次皮下注射,另一组使用胰岛素泵持续皮下注射速效胰岛素类似物。结果患者的8个点血糖(空腹血糖,三餐后2h血糖,午、晚餐前血糖,22:00、03:00血糖)和糖化血红蛋白A1c均达到目标值,且胰岛素泵组最短血糖达标只需要20 h。结论这两种注射方法均能获得良好的血糖控制;多次皮下注射相对胰岛素泵稍经济(但差异无统计学意义);使用胰岛素泵的患者依从性更好。Objective To compare the safety, efficiency and compliance between using different kinds of insulin analogue and different kinds of administration in new patients with diabetes. Methods 100 diabetic patients were involved and randomly assigned to two different groups, the states of patients were evaluated after re- ceiving either insulin analogue（short and long-acting） via subcutaneous injection（ n = 50） or short-acting insulin analogues via insulin pump（ n = 50）, in order to compare the efficiency of each administration form. Results It was showed that eight-point（before and after three meals, at bedtime and 3AM ）blood glucose proflie and HbAle value had recovered to the normal level. Especially when using the insulin pump, this recovery time was only 20 hrs. Conclusions These two administration forms can both control blood glucose. Continuous subcutaneous injection was cheaper（no statistic difference）, while the patient compliance by using insulin pump was better.

关 键 词：糖尿病 胰岛素类似物 皮下注射 胰岛素泵 

分 类 号：R587.1[医药卫生—内分泌]