皮下埋植避孕剂左旋18甲基炔诺酮Ⅰ型体内释药速率及其影响因素  

Study on release rate in vivo and influence factors of Norplant ○[KG-*5/6]R Ⅰ contraceptive implant

作　　者：李家仁[1] 张虹[1] 翟所迪[1] 高云丽[1] 蒲瑞征 高英敏[1] 

机构地区：[1]兰州医学院第一附属医院

出　　处：《中国医院药学杂志》1997年第3期121-123,共3页Chinese Journal of Hospital Pharmacy

摘　　要：采用紫外分光光度法测定了左旋１８甲基炔诺酮皮下埋植避孕剂Ⅰ型（Ｎｏｒｐｌａｎｔ○ＲⅠ）埋植３～１１１个月体内药物释放速率，其结果与美国人口理事会报道相近，并考察了体重、年龄因素对释药速率的影响。实验表明，此长效埋植剂的释药速率不受体重、年龄因素影响。The release rate of Norplant ○R Ⅰ for implant 3-111 monthes in vivo was determined using a UV spectrophotometry at 240nm ( n =120).The result was similar to the reports of the american population council.The effect of weight and years on release rate was studied.The results showed that weight and age had no influence on release rate.

关 键 词：避孕药 皮下埋植剂 甲基炔诺酮Ⅰ 体内释药速度 

分 类 号：R979.21[医药卫生—药品]