以Pluronics~为第二组分制备聚乳酸蜂窝状规整多孔薄膜  

Preparation of Ordered and Porous Honeycomb Structure Film of Poly(lactic acid) with Pluronics~ as the Second Component

作　　者：孙巍[1] 唐越超[1] 计剑[1] 

机构地区：[1]浙江大学高分子科学与工程学系教育部高分子合成与功能构造重点实验室,杭州310027

出　　处：《高等学校化学学报》2007年第7期1388-1392,共5页Chemical Journal of Chinese Universities

基　　金：国家重点基础研究规划项目(批准号:2005CB623902);教育部"新世纪优秀人才计划"(批准号:NCET-05-0527)资助

摘　　要：以聚乳酸(PLA)为成膜材料,以两亲三嵌段共聚物PEO-PPO-PEO(Pluronics)为第二组分,利用水辅助法成功地制备了聚乳酸蜂窝状多孔膜.研究了环境湿度、溶液浓度和所用PLA分子量对多孔膜结构的影响.结果表明,加入第二组分PEO-PPO-PEO能有效地促进规整蜂窝结构的形成.蛋白质吸附实验结果进一步证明了PEO-PPO-PEO组分在孔洞内壁的富集,由此构建了阻抗蛋白质吸附的图案化功能结构表面.A porous poly （lactic acid） film with a well-ordered honeycomb structure was prepared via the breath-figure method. The addition of amphiphilic Pluronics was proved to be able to benefit a lot to fabricate the well-ordered honeycomb-patterned film. Several influencing factors including atmosphere humidity, solution concentration and the molecular weight were investigated. The fluorescein isothiocyanate labelled bovine serum albumin（FITC-BSA） was used as the probes to investigate the protein absorption onto the pattern film. Fluorescence images showed the corresponding honeycomb patterns, indicating that the honeycomb-patterned films with protein-resistant pores could be successfully constructed with Pluronics as the second component.

关 键 词：水辅助法组装 蜂窝状结构 聚乳酸 两亲三嵌段共聚物(PEO-PPO-PEO) 

分 类 号：O631[理学—高分子化学] O647[理学—化学]