比格犬埃立克体病实验模型研究 Ⅲ病原观察  

Study on Experimental Model of Ehrlichiosis in Beagle Dogs Ⅲ.The Examination of Pathogen

作　　者：刘世忠[1] 马玉海[2] 刘广江[3] 黄俊明[4] 曾昭智[1] 赵乐[1] 顾为望[1] 

机构地区：[1]南方医科大学实验动物中心,广东广州510515 [2]广州军区疾病预防控制中心,广东广州510507 [3]广州市公安局巡警支队警犬基地,广东广州510410 [4]广东省疾病预防控制中心,广东广州510300

出　　处：《动物医学进展》2007年第7期43-45,共3页Progress In Veterinary Medicine

基　　金：总后勤部面上课题(01MB035);广东省科技计划项目(2005B60302007)

摘　　要：为了观察犬埃立克体病病犬血细胞中病原的感染情况,对6只人工感染埃立克体的比格犬血细胞进行了光镜和透射电镜观察。结果发现,单核细胞的细胞质和血小板中均存在埃立克体包涵体,其中单核细胞的包涵体内病原多达8个,血小板的包涵体内也发现数个病原。这一结果进一步证实我们成功地建立了比格犬埃立克体病实验模型,也为临床上诊断犬埃立克体病提供了形态学依据。To investigate infectious state of pathogen in blood cell on beagle dogs infected with Ehrlichia, blood samples from 6 beagle dogs artificially infected with Ehrlichia Canis and Ehrlichia Platys were examined through light microscopy and electron microscopy. The result showed that the pathogens were in cytoplasmic vacuoles of mononuclear cells and platelets, with more as 8 pathogen cytorrhyctes in cytoplasmic vacuoles of mononuclear cells and no more than 3 in platelets. The results proved the successful found of beagle dogs ehrlichiosis laboratory model, which can also contribute a lot to clinical dog ehrlichiosis diagnosis.

关 键 词：比格犬 埃立克体病 病原 检查 

分 类 号：S852.31[农业科学—基础兽医学]