阻塞性睡眠呼吸暂停低通气综合征与男性不育症  

Association of male infertility with obstructive sleep apnea hypopnea syndrome

作　　者：樊利萍[1] 王蓓[1] 刘卓拉[1] 

机构地区：[1]山西医科大学第二临床医学院呼吸科,太原030001

出　　处：《山西医科大学学报》2007年第7期624-626,共3页Journal of Shanxi Medical University

基　　金：山西省卫生厅科技攻关项目(200407)

摘　　要：目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与男性不育的关系。方法对重度OSAHS患者16例使用持续气道正压(CPAP)呼吸机治疗前后进行检查,其内容包括精液及性激素水平,并随访其生育情况。结果随访的16例患者使用CPAP机治疗后有11例生育正常小儿,且精液检查及激素水平测定均较治疗前有明显好转,表现为精子浓度、精子活力较治疗前明显增加,去氢睾酮及黄体生成素水平均较治疗前明显增高,治疗前后相比差异有显著性(P<0.05)。结论OSAHS可能是男性不育的原因之一。Objective To investigate the relationship between male infertility and obstructive sleep apnea hypopnea syndrome（OSAHS）. Methods The level of gonadal hormone and semen of 16 patients with severe OSAHS were measured before and after the continuous positive airway pressure（CPAP） therapy. The patients were followed-up. Results In 16 patients with CPAP therapy, 11 cases had normal baby born, and the levels of the gonadal hormone and semen were significantly improved after treatment. Sperm concentration and the motility of sperm significantly increased, and the levels of dehydrotestosterone and luteinizing hormone were significantly higher than that before treatment （P〈 0.05）. Conclusion OSAHS might be one of the courses of male infertility.

关 键 词：不育 男性 阻塞性睡眠呼吸暂停低通气综合征 男性不育症 持续气道正压通气 

分 类 号：R689.2[医药卫生—骨科学]