丝素/胶原蛋白共混纳米纤维的结构分析  

Structural Analysis of Silk Fibroin and Collagen Blended Nanofiber

作　　者：王曙东[1] 吴佳林[1] 张幼珠[1] 

机构地区：[1]苏州大学材料工程学院,江苏苏州215021

出　　处：《丝绸》2007年第7期22-24,共3页Journal of Silk

基　　金：江苏省高校重点实验室开放研究课题(S8115033)

摘　　要：采用桑蚕废丝制作再生丝素室温干燥膜,并以不同质量比例与水溶性胶原蛋白混合,溶解于质量分数为98%的甲酸中制得不同质量分数的纺丝液,选择一定的工艺参数进行静电纺丝。通过扫描电镜观察纳米纤维的外观形貌并计算纤维平均直径,采用红外光谱测定纳米纤维的微细结构。结果表明:纳米纤维的直径随着纺丝液质量分数和丝素与胶原蛋白共混质量比例的提高而增大;水溶性胶原蛋白与丝素之间有相互作用,纯丝素电纺纳米纤维结构以无规构象为主,含有少量β折叠,丝素/胶原蛋白共混纳米纤维β化程度提高。Regenerated silk fibroin （SF） membrane was prepared by using waste silk at room temperature.The membrane was mixed with water-solubility collagen at various concentrations,and dissolved in 98% formic acid to make various concentrations of spinning solution.Electrospinning was implemented in determinate technological parameters.The morphology and diameter of the nanofibers were observed by SEM;and the microstructure was tested by means of IR Spec trum.The results show that the diameter of nanofibers increases with the increase of concentration of spinning solution and composition ratio of SF/collagen.There is reciprocity between SF and water-solubility collagen,the conformation of SF nanofibers mainly exhibits random coil and have less β-sheet and the β-sheet conformation of SF/collagen increases.

关 键 词：再生丝素 水溶性胶原蛋白 静电纺丝 纤维形貌 纤维直径 微细结构 

分 类 号：TS149[轻工技术与工程—纺织材料与纺织品设计]