Second pregnancy of trisomy 21 in a mother with mosaicism  

作　　者：CUI Ying-xia HAO Li-jun WANG Yun-hua XIA Xin-yi SHI Yi-chao LU Hong-yong YAO Bing HUANG Yu-feng 

机构地区：[1]Department of Reproduction and Genetics, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing 210002, China

出　　处：《Chinese Medical Journal》2007年第14期1295-1296,共2页中华医学杂志（英文版）

摘　　要：In the case of a previous offspring with trisomy 21, recurrence risk for Down syndrome is about 1%. It may be due to chance, but the possibility of germline mosaicism for trisomy 21 in one of the parents has important implications for the recurrence. Here we report a young healthy mother, who has a second pregnancy of trisomy 21.In the case of a previous offspring with trisomy 21, recurrence risk for Down syndrome is about 1%. It may be due to chance, but the possibility of germline mosaicism for trisomy 21 in one of the parents has important implications for the recurrence. Here we report a young healthy mother, who has a second pregnancy of trisomy 21.

关 键 词：trisomy 21 MOSAICISM microsatellite markers 

分 类 号：R71[医药卫生—妇产科学]