儿童药物超敏综合征9例临床分析  

Clinical Characteristics of Children Drug Hypersensitivity Syndrome

作　　者：汤建萍[1] 树叶[1] 韦祝[1] 曾迎红[1] 

机构地区：[1]湖南省儿童医院,湖南长沙410007

出　　处：《中国皮肤性病学杂志》2007年第7期412-413,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨儿童药物超敏综合征的临床特点。方法回顾性分析了9例住院儿童药物超敏综合征的临床资料和随访结果。结果9例患儿均出现发热、全身皮疹、浅表淋巴结肿大和内脏损害。致敏药物苯巴比妥6例、卡马西平4例、磺胺嘧啶和阿司匹林各1例。随访时均已痊愈。结论儿童药物超敏综合征以发热、皮疹、淋巴结肿大和内脏损害为特征,致敏药物以抗惊厥药为主。Objective To explore the clinical features and summarize of Drug Hypersensitivity Syndrome （DHS）. Methods Nine children with DHS hospitalized were analyzed and followed up. Results All patients had fever, skin rash, lymphadenomegaly and internal organ involvement. Sensitization drugs were Phenobarbital （ n = 6）, carbamazepine （ n = 4 ）, sulfadiazine （ n = 1 ） and aspirin （n = 1 ）. All of the cases was recovery. Conclusion DHS in children was characterized by fever, rash,lymphadenomegaly and internal organ damaged. The principal sensitization drugs were anticonvulsants.

关 键 词：药物超敏综合征 儿童 

分 类 号：R758.25[医药卫生—皮肤病学与性病学]