2型糖尿病患者血清高敏C反应蛋白与大血管病变的相关性研究  

Relationship between Serum Hypersensitivity C-Reactive Protein and Macrovascular Diseases in Type 2 Diabetic Patients

作　　者：陶少平[1] 周蓓[1] 杭宇[1] 陈学峰[1] 

机构地区：[1]皖南医学院第二附属医院内分泌科,安徽省芜湖市241000

出　　处：《实用全科医学》2007年第8期672-673,共2页Applied Journal Of General Practice

摘　　要：目的探讨2型糖尿病患者血清高敏C反应蛋白(hsC-RP)与大血管病变的关系。方法选择2型糖尿病患者68例,其中2型糖尿病并发大血管病变组(A组)36例,无大血管病变组(B组)32例,并选择30例健康者为对照组(C组)。分别测定3组患者血清hsC-RP水平。结果A组和B组血清hsC-RP水平均高于C组,A组明显高于B组。结论血清hsC-RP水平的检测对预测2型糖尿病大血管病变的发生发展有重要的临床意义。Objective To explore the relationship between hypersensitivity C-reactive protein （hsC-RP） and diabetic macrovascular diseases. Methods 68 cases with type 2 diabetes were divided into two group ： Group A （ n = 36） was with macrovascular complication and Group B （n = 32） without. 30 healthy subjects were selected as control （Group C）. The serum hsC-RP was determined by immunoturbidimetry. Results The level of hsC-RP in group A was significantly higher than that in group B and C. Conclusions The hsC-RP may play an important role in the pathogenesis of diabetes mellitus and its macrovascular complication and can be applied to predict the development of macrovascular diseases as an early predicator.

关 键 词：糖尿病 2型 C反应蛋白 大血管病变 

分 类 号：R587.1[医药卫生—内分泌] R543.5[医药卫生—内科学]