血清总胆汁酸测定在肝胆疾病中的临床意义  

Role of Serum Total Bile Acid Determination in Diagnosis and Treatment of Liver and GallBladder Diseases

作　　者：倪文伟[1] 顾猛[1] 曹小秋[1] 

机构地区：[1]江苏省南通瑞慈医院检验科,226010

出　　处：《实用全科医学》2007年第8期736-737,共2页Applied Journal Of General Practice

摘　　要：目的通过对血清总胆汁酸水平的检测来观察其在肝胆疾病诊治中的临床意义。方法采用全自动生化分析仪对142例肝胆疾病患者及135名健康体检者进行血清总胆汁酸和常规肝功能检测。结果正常对照组的总胆汁酸的参考范围为0．6～15．8μmol／L，其（x^-±s）为（2．9±0．9）μmol／L，而患者组血清总胆汁酸参考范围为1．3～238．0μmol／L，（x^-±s）为（100±63）μmol／L，与正常对照组差异有统计学意义，且其灵敏度和特异性明显优于其他肝功能指标。结论血清总胆汁酸水平的测定在肝胆疾病的诊断、治疗及预后判断中有重要意义。Objective To determine the clinical significance of serum total bile acid（TBA） d6termination in the diagnosis and treatment of liver and gallbladder diseases. Methods Serum TBA and other liver function related items were determined with automatic biochemistry analyzer in 142 cases with liver and gall bladder diseases and 135 healthy people （as control）. Results The serum TBA level was 0.6 - 15.8 μmol/L in the control group,and 1.3 -238.0 μmol/L in the patient group,and there was significant difference between the two groups. The sensitivity and specificity of TBA was better than other liver function items. Conclusions Serum TBA level determination is important in the diagnosis,treatment and prognosis predict of liver and gallbladder diseases.

关 键 词：总胆汁酸 肝胆疾病 肝功能 

分 类 号：R446.11[医药卫生—诊断学]