胰岛素敏感性与冠状动脉弥漫性病变的关系  

Correlation between insulin sensitivity and diffuse lesion in coronary artery

作　　者：陶剑虹[1] 李刚[1] 贺涛[1] 刘明江[1] 罗莹[1] 黄启华[1] 李杰[1] 

机构地区：[1]四川省医学科学院四川省人民医院心内科,610072

出　　处：《国际心血管病杂志》2007年第4期297-298,共2页International Journal of Cardiovascular Disease

摘　　要：目的:研究胰岛素敏感性与冠状动脉弥漫性病变的关系。方法:138例患者行葡萄糖耐量试验并择期行冠状动脉造影。根据冠脉造影结果,将患者分为冠脉弥漫病变组、冠脉非弥漫病变组和冠脉正常组。分析冠状动脉病变情况与胰岛素敏感性的关系。结果:冠脉弥漫病变组与非弥漫病变组的胰岛素敏感指数(ISI)差异有显著性(-4.36±0.52对-3.89±0.69,P<0.01),且与冠脉正常组的ISI(-2.78±0.58)差异也有显著性意义。结论:冠心病患者的胰岛素敏感性与其冠状动脉病变弥漫程度有密切关系。Objective： To investigate the correlation between insulin sensitivity and diffuse lesion in coronary artery. Methods：One hundred and thirty-eight patients were tested the glucose to lerance and were performed the coronary angiograpby. Divied the patients to diffuse coronary artery disease group, non diffuse coronary artery disease group and normal group according to the angiograpby, then the relationship between coronary artery disease and glucose tolerance were analyzed. Results：The insulin sensitivity index （ISI） of diffuse coronary artery disease group was -4. 36±0.52, ISI of non diffuse coronary artery disease was - 3.89 ±0.69,ISI of normal gronp was - 2.78 ± 0.58, P〈0.01. Conclusion：The insulin sensitivity in patients with coronary artery disease were related to the diffuse degree of coronary artery disease.

关 键 词：胰岛素敏感性 冠心病 弥漫性病变 

分 类 号：R541.4[医药卫生—心血管疾病]