广西肝癌高发农村地区人群HBsAg肝病患病筛查现况分析  

Analysis of incidence of hepatic diseases in population of anti-cancer screening and HBsAg positives in rural areas of Guangxi

作　　者：张春燕[1] 黄天壬[1] 余家华[1] 利基林 何振芳[1] 周德南[1] 叶司原[1] 邓伟[1] 盛鹰[1] 翟红艳 赵盛发[1] 张振权[1] 梁安民[1] 唐步坚[1] 

机构地区：[1]广西壮族自治区肿瘤防治研究所,广西南宁530021

出　　处：《中国热带医学》2007年第8期1316-1318,共3页China Tropical Medicine

基　　金：中国癌症研究基金会资助项目(No2006009);广西省科技攻关项目(桂科攻0632007-10)

摘　　要：目的分析对比广西肝癌高发农村地区防癌筛查人群及其HBsAg阳性人群的常见肝病的流行特点和分布特征。方法选择广西肝癌高发农村地区20岁以上常住居民(15701人)作为研究对象,进行现场流行病学调查、血清生化指标检测、肝脏B超检查和体格检查等,并与其中HBsAg阳性人群(2800人)进行对比分析。结果防癌筛查人群HBsAg阳性率为17.83%,其中男性为20.21%,女性为13.18%,男性HBsAg阳性率明显高于女性。在整个防癌筛查人群,肝占位、肝硬化、肝吸虫感染、脂肪肝、酒精肝和肝大等患病率较高,均男性检出率明显高于女性。防癌筛查HBsAg阳性人群的肝占位、肝硬化、肝炎和肝吸虫感染,男性检出率均明显高于女性,且肝炎、肝硬化和肝占位的检出率明显高于防癌筛查人群。结论广西肝癌高发地区的肝炎、肝硬化和肝占位的患病主要与HBV高感染有关,肝吸虫感染、脂肪肝、酒精肝等常见肝病也同时呈现高患病率状况,尤其男性成年人群是肝病高危人群。各级政府、卫生行政部门对广西肝癌高发农村地区的肝病现状必须高度重视,并采取有效防治措施。Objective To analyze the epidemiological characteristics of common hepatopathy among the rural population in areas highly prevalent with primary liver cancer （PLC） in Guangxi Zhuang Autonomous Region. Methods There 1 5701 adults inhabitants aged over 20 years old in rural areas were epidemiologically screened for cancer on the spot by measns of cross - sectional study and their peripheral blood sera were collected and tested with HBsAg Enzyme immunoassays, and their liver morphological changes were measured with ultrasonngraphy. In addition, physical examinations were also conducted. Results The HBsAg positive rates of total population,males and females surveyed were 17.83%, 20.21% and 13.18%, respectively, being higher in the males than that of females. The prevalence ratcs of PLC, hepatocirrhosis, elonorchis sinensis, fatty liver, alcoholic hepatitis and hepatomegaly in males among the cancer prevention screening population were significantly higher than that of females. Among the cancer prevention screening population whose HBsAg were positive, the prevalence rates of PLC, hepatocirrhosis, hepatitis, elonorchis sinensis were significantly higher in males than that of females. The prevalence rates of hepatitis, hepatocirrhosis and PLC were significantly higher among the cancer prevention screening population postive for HBsAg than that of cancer prevention screening population. Conclusion In this high PLC prevalence region the high prevalence rates of hepatitis, hepatocirrhosis and PLC are associated with the high prevalence rate of hepatitis B virus. The prevalence rates of elonorchiasis, fatty liver, alcoholic hepatitis were also high. Thus high attention be paid to the control of hopatppathy in areas highly prevalent with liver cancer in rualral aeas of Guangxi by the local Govennnents at various levels and effective measures be taken for prevention and treatment of the diseases.

关 键 词：现况研究 流行特征 肝病 患病率 原发性肝癌 

分 类 号：R512.62[医药卫生—内科学]