4,5-二氢-3-甲基-1-(4-氯-2-氟苯基)-4-二氟甲基-1,2,4-三唑-5(1H)酮的合成方法  

Synthesis of 4,5-dihydro-3-methyl-1-(4-chloro-2-fluorophenyl)-4-difluoromethyl-1,2,4-triazol-5-(1H)-one

作　　者：何普泉[1] 王传品[1] 苏朝辉[1] 王广强[1] 

机构地区：[1]安徽丰乐农化有限责任公司,安徽合肥230031

出　　处：《安徽化工》2007年第3期19-20,共2页Anhui Chemical Industry

摘　　要：4,5-二氢-3-甲基-1-(4-氯-2-氟苯基)-4-二氟甲基-1,2,4-三唑-5(1H)酮是超高效含氟除草剂唑酮草酯的重要中间体,采用高温氟化的方法,通过优化反应条件,使目标化合物的合成收率达75.4%,含量达97.3%,降低了成本,更利于工业化生产。Adopting the technique of elevated temperature fluoration and optimizing the rdaction condition,the synthetic yield of 4,5-dihydro-3-methyl- 1-（4-chloro-2-fluorophenyl ）--4-difluoromethyl- 1,2,4-triazol-5-（ 1H）-one was improved to 75.7% and the content reached 97.3%. This technique reduced production cost and good for industrialization. This compound was an important intermediate to synthesize carfentrazon e-ethyl,a super high effective herbicide.

关 键 词：4 5-二氢-3-甲基-1-(4-氯-2-氟苯基)-4-二氟甲基-1 2 4-三唑-5(1H)酮 唑酮草酯 中间体 高温氟化 

分 类 号：TQ457.21[化学工程—农药化工]