藏药“生等”中墨沙酮成分的超临界CO_2萃取工艺研究  

SUPERCRITICAL CO_2 FLUID EXTRACTION OF MAESOPSIN FROM Rhamnella gilgitica

作　　者：姜继祖[1] 杨培全[1] 廖周坤[1] 晁若冰[1] 叶开润[1] 张印俊[1] 辛复泰[2] 杨儒逵[2] 

机构地区：[1]华西医科大学药学院,成都610041 [2]四川省机械研究设计院,成都610041

出　　处：《华西药学杂志》1997年第1期35-37,共3页West China Journal of Pharmaceutical Sciences

基　　金：国家自然科学基金;四川省科委应用基础研究基金

摘　　要：用超临界CO2流体萃取法对藏药“生等”（RhamnellagilgilitcaMansf．etMelch．）的主要成分墨沙酮（Maesopsin）的萃取进行了研究，探讨了压力、温度、夹带剂流量对革取效率的影响；并用HPLC法作了含量测定．结果表明，本法提取率约为超声波军取法的1．2倍。A Study on supercritical CO2, fluid extraction of maesopsin (Ⅰ ), a major constituent of Shengdeng (Rhamneta gilgitica Mansf. et Melch, Rhamnaceae ), a traditional Tibetan medicinal herb, was made. The parameters innuencing the extraction efficiency including temperature, pressure and the volumes of entrainer were investigated. The assay of (Ⅰ ) was performed by HPLC. The results showed tbat CO2,-SFE was about 1. 2 times as extraction rate of ultrasonic extraction.

关 键 词：萃取 西藏猫乳 墨沙酮 HPLC 生等 

分 类 号：R284.2[医药卫生—中药学] R291.4[医药卫生—中医学]