冷冻切片诊断子宫内膜病变4541例分析  

A Retrospective Analysis of 4541 Frozen Section from Endometrial Curettings

作　　者：孙亮[1] 杨开选[1] 杨帆[1] 徐炼[1] 黄芹[1] 宋波[1] 张燕[1] 

机构地区：[1]四川大学华西第二医院病理科,四川成都610041

出　　处：《华西医学》2007年第3期515-516,共2页West China Medical Journal

摘　　要：目的:探讨冰冻切片病理诊断对子宫内膜病变诊断的价值。方法:回顾分析2002～2006年间四川大学华西第二医院4541例子宫内膜病变冰冻切片诊断与石蜡切片诊断符合情况。结果:利用冷冻切片诊断子宫内膜病变,确诊率95.72%,误诊率2.36%,未能确诊率1.92%。误诊107例,主要见于子宫内膜良性病变;只有1例坏死严重的良性病变被误诊为恶性肿瘤。误诊原因中,读片有误59.43%,制片不良40.57%。结论:冷冻切片是快速确诊子宫内膜病变的有效方法。提高取材和制片技术、掌握冷冻切片的镜下特征,冷冻切片诊断子宫内膜病变可行。Objective： The 4541 cases of endometrial curettings were analysed from their frozen sections （FS） and paraffin sections in order to evaluate the value of frozen sections for the diagnosis of endometrial lesions. Methods： A retrospective analysis of the pathologic database of the Department of Obstetrics and Gynecology in our institute was performed during January 2001 to December 2006, in order to determine the accuracy of frozen section diagnosis in endometrial lesions. The results of frozen section diagnosis of 4541 cases were compared with the final diagnosis of paraffin sections. Result： Total coincident rate of FS was 95.72%, misdiagnosed rate was 2.36%, failure rate was 1.92%. In 107 cases misdiagnosed cases, only one case was misdiagnosed as malignant tumor because of several necrosis. Besides misdiagnosis, interpretation error accounted to 59.43 %, and poorly made sample section for 40.57%. Conclusion： Frozen section was a rapid and accurate method in histological diagnosis of endometrial lesions. Improving sampling technique, mastering the gross appearances and microscopic features of difficult cases could increase the accuracy of diagnosis of frozen section for endometrial lesions.

关 键 词：子宫内膜病变 冷冻切片 快速诊断 

分 类 号：R711.7[医药卫生—妇产科学]