The Villin/Gelsolin/Fragmin Superfamily Proteins in Plants  

作　　者：Hui Su Ting Wang Huaijian Dong Haiyun Ren (Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education and College of Life Sciences Beijing Normal University Beijing 100875 China 

出　　处：《Journal of Integrative Plant Biology》2007年第8期1183-1191,共9页植物学报（英文版）

基　　金：Supported by the National Natural Science Foundation of China (30630005,30470176 and 30325005);the State Key Basic Research and Development Plan of China (2006CB100100).

摘　　要：The villin/gelsolin/fragmin superfamily is a conserved Ca^2＋-dependent family of actin-regulating proteins that is widely present both in mammalian and non-mammalian organisms. They have traditionally been characterized by the same core of three or six tandem gelsolin subdomains. The study in vertebrates and lower eukaryotic cells has revealed that the villin/gelsolin/fragmin superfamily of proteins has versatile functions including severing, capping, nucleating or bundling actin filaments. In plants, encouraging progress has been made in this field of research in recent years. This review will summarize the identified plant homologs of villin/gelsolin/fragmin superfamily, thus providing a basis for reflection on their biochemical activities and functions in plants.The villin/gelsolin/fragmin superfamily is a conserved Ca^2＋-dependent family of actin-regulating proteins that is widely present both in mammalian and non-mammalian organisms. They have traditionally been characterized by the same core of three or six tandem gelsolin subdomains. The study in vertebrates and lower eukaryotic cells has revealed that the villin/gelsolin/fragmin superfamily of proteins has versatile functions including severing, capping, nucleating or bundling actin filaments. In plants, encouraging progress has been made in this field of research in recent years. This review will summarize the identified plant homologs of villin/gelsolin/fragmin superfamily, thus providing a basis for reflection on their biochemical activities and functions in plants.

关 键 词：actin-binding protein actin cytoskeleton Villin/Gelsolin/Fragmin. 

分 类 号：Q946.1[生物学—植物学]