[Cu(H_2bzimpy)(Gly)]NO_3·H_2O的合成、表征及其与DNA作用的研究  

Synthesis,Characterization and Interaction with DNA of Copper(Ⅱ) Complex with 2,6-Bis(Benzimidazy-2′) Pyridine and Glycine

作　　者：宋昭凤[1] 肖小明[1] 朱艳华[1] 

机构地区：[1]湖南师范大学化学化工学院,长沙市麓山南路410081

出　　处：《光谱实验室》2007年第4期722-724,共3页Chinese Journal of Spectroscopy Laboratory

基　　金：湖南省教育厅重点课题(03A026)资助项目

摘　　要：合成并表征了铜配合物[CuL(Gly)]NO3·H2O(L=6-二(苯并咪唑-2′)吡啶(H2bzimpy);Gly为甘氨酸(Glycine)。利用电子吸收光谱、荧光光谱和粘度等方法研究了配合物与DNA的作用,结果表明配合物以部分插入模式与DNA相互作用。The copper（Ⅱ） complexe [CuL（Gly）]NO3·H2O was synthesized and characterized by UV, infrared spectroscopy and fluorescence spectra, where L is 2,6-bis（henzimidazy-2＇ ）pyridine, gly is glycine. The binding of the complex with calf thymus DNA was investigated by UV, fluorescence spectra and viscosity measurements. The complex binds to DNA base pairs by partial intercalate.

关 键 词：苯并咪唑 铜配合物 DNA键合 

分 类 号：O657.32[理学—分析化学]