老年高血压颈动脉粥样硬化与心血管危险因素的相关性研究分析  

Relationship between carotid arterial atherosclerosis and cardiovascular risk factors in elderly patients with hypertension

作　　者：杨建芬[1] 李蔚[1] 孙宜萍[1] 

机构地区：[1]上海交通大学附属第六人民医院老年科,上海市200233

出　　处：《实用老年医学》2007年第4期236-239,共4页Practical Geriatrics

摘　　要：目的研究老年高血压患者颈动脉粥样硬化、斑块形成与心血管危险因素以及脑卒中发生之间的相关性。方法随机调查204例老年高血压患者,用颈动脉超声检查分析颈动脉硬化、斑块形成与心血管病危险因素及脑卒中的相关性。结果颈动脉硬化、斑块形成与收缩压、脉压呈正相关(r=0.21、0.26,P<0.01),与高血压病程、糖化血红蛋白(HbA1c)亦呈正相关(r=0.17、0.30,P<0.05),与尿酸、胆红素、高密度脂蛋白胆固醇(HDL-C)及脑卒中均有关。结论上述心血管危险因素在老年人颈动脉粥样硬化、斑块形成的发生、发展中起到一定的作用,控制这些危险因素有益于减少脑卒中发生。Objective To study the relationship between carotid arterial atherosclerosis, plaque and various cardiovascular risk factors, stroke in aged patients with hypertension. Methods 204 elderly patients with hypertension undergoing carotid artery ultrasonography were enrolled, then the relationship of carotid arterial atherosclerosis, plaque with various cardiovascular risk factors and stroke were analyzed. Results Carotid arterial atherosclerosis and plaque showed positive correlation with systolic pressure and pulse pressure（ r = 0. 21,0. 26 ,P 〈 0. 01 ） and with the course of hypertension and glycosylated hemoglobin （ HbA1 c ） （ r = 0. 17,0. 30, P 〈 0. 05 ） , and were associated with the level of serum uric acid, bilirubin, high-density lipoprotein cholesterol（HDL-C） and the development of stroke. Conclusions Above-mentioned cardiovascular risk factors may play a role in the development of atherosclerosis and plaque in aged people.

关 键 词：颈动脉超声 动脉粥样硬化 心血管危险因素 脑卒中 

分 类 号：R543[医药卫生—心血管疾病]