Highly Efficient Pd/C-Catalyzed Suzuki Coupling Reaction of p-（un）Substituted Phenyl Halide with （p-Substituted phenyl） Boronic Acid  

作　　者：胡明刚 安忠维 杜渭松 李建 高嫒嫒 

机构地区：[1]Optical and Electrical Material Center, Xi'an Modern Chemistry Research Institute, Xi'an, Shaanxi 710065, China

出　　处：《Chinese Journal of Chemistry》2007年第8期1183-1186,共4页中国化学（英文版）

摘　　要：A highly efficient Pd/C-catalyzed ligandless, heterogeneous Suzuki reaction of p-（un）substituted phenyl halide with （p-substituted phenyl）boronic acid in DMF/H2O solvent in a short reaction time （0.5 h） at 75 ℃ was developed. The key for such a catalytic system was the addition of 1 equivalent of tetrabutylammonium bromide. A wide variety of substituents can be tolerated and high yields of cross coupling products were achieved. The palladium catalyst can be easily recovered and reused without significantly decreasing its efficiency.A highly efficient Pd/C-catalyzed ligandless, heterogeneous Suzuki reaction of p-（un）substituted phenyl halide with （p-substituted phenyl）boronic acid in DMF/H2O solvent in a short reaction time （0.5 h） at 75 ℃ was developed. The key for such a catalytic system was the addition of 1 equivalent of tetrabutylammonium bromide. A wide variety of substituents can be tolerated and high yields of cross coupling products were achieved. The palladium catalyst can be easily recovered and reused without significantly decreasing its efficiency.

关 键 词：Suzuki coupling PD/C TBAB 

分 类 号：O627.31[理学—有机化学]