良性前列腺增生超声造影的初步研究  

A Preliminary Study of Contrast-enhanced Ultrasound in Benign Prostatic Hyperplasia

作　　者：唐杰[1] 王知力[1] 李俊来[1] 罗渝昆[1] 汪伟[1] 徐建宏[1] 石怀银[2] 

机构地区：[1]中国人民解放军总医院超声科,北京100853 [2]中国人民解放军总医院病理科,北京100853

出　　处：《中华男科学杂志》2007年第7期584-587,共4页National Journal of Andrology

基　　金：国家自然科学基金(30670549)

摘　　要：目的:分析并评价BPH的超声造影表现,探讨超声造影对研究BPH血流灌注的价值。方法:对48例经直肠超声引导下穿刺活检、病理证实为BPH的患者进行超声造影检查,观察前列腺内腺及外腺的超声造影表现并制作时间-强度曲线,分析超声造影开始增强时间、造影开始减退时间、造影剂渡越时间及峰值强度。结果:前列腺为富血供器官,造影增强明显。48例BPH患者前列腺内腺及外腺开始增强的时间分别为(26.68±3.76)、(31.24±5.33)s,内腺开始增强的时间显著早于外腺,尤以尿道周围区及内腺的包膜处明显(P=0.000);内腺及外腺造影剂完全退出时间分别为(200.68±59.40)、(157.56±50.66)s,内腺造影剂完全退出时间显著晚于外腺(P=0.000);内腺及外腺造影剂渡越时间分别为(173.94±60.14)、(129.21±56.91)s,内腺造影剂渡越时间显著长于外腺(P=0.000)。内腺及外腺造影峰值强度分别为(90.45±42.19)、(65.32±25.15)dB,内腺造影峰值强度显著高于外腺(P=0.000)。结论:超声造影检查能够连续观察BPH的血流灌注情况,有望成为研究BPH血流状况的有效方法。Objective ： To analyze and evaluate the characteristics of benign prostatic hyperplasia （BPH） on contrast-enhanced ultrasound. Methods： Forty-eight BPH patients confirmed by transrectal ultrasound-guided biopsy underwent contrast-enhanced ultrasound. Contrast pulse sequencing technique （CPS） and quantitative software-ACQ were used, and the parameters of beginning enhancement time, disappearing and transit time and peak intensity （PI） of the inner gland and outer gland were recorded and analyzed. Results： The prostate was rich with blood and enhanced significantly on contrast-enhanced ultrasound. The beginning enhancement time of the prostatic inner gland, especially the area around the urethra, was much earlier than that of the outer gland, （ 26.68 ± 3.76） and （31.24 ± 5.33） s, respectively （P = 0. 000）. The contrast disappeared later in the inner gland than in the outer gland, （200.68 ± 59.40 ） and （ 157.56 ± 50.66 ） s, respectively （P = 0. 000）. The transit time of the contrast in the inner gland was much longer than in the outer gland, （ 173.94 ± 60.14） and （ 129.21 ± 56.91 ） s, respectively （P = 0.000）. PI of the inner gland was much higher than that of the outer gland, （90.45 ±42.19） and （65.32 ±25.15） dB, respectively （P =0.000）. Conclusion： Contrast-enhanced ultrasound makes it possible to continuously observe the blood perfusion process of BPH, and promises to be an effective means for observing the blood supply in BPH.

关 键 词：良性前列腺增生 超声 造影 

分 类 号：R697.3[医药卫生—泌尿科学] R445.1[医药卫生—外科学]