Unexpected anterograde amnesia associated with Buscopan used as a predmedication for endocscopy  

作　　者：Hyuk Lee Hee Jung Son Poong-Lyul Rhee Jae J Kim Jong Chul Rhee 

机构地区：[1]Departments of Medicine,Samsung Medical Center,Sungkyunkwan University School of Medicine,Seoul 135-710,Korea [2]Departments of Medicine,Samsung Medical Center,Sungkyunkwan University School of Medicine,Seoul 135-710,Korea Center for Health Promotion,Samsung Medical Center,Sungkyunkwan University School of Medicine,Seoul 135-710,Korea

出　　处：《World Journal of Gastroenterology》2007年第28期3895-3896,共2页世界胃肠病学杂志（英文版）

摘　　要：It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide (Buscopan; Boehringer Ingelheim, Germany) used as a premedication for endoscopy. However, symptoms or signs associated with the central nervous system are rarely reported in the field of anesthesiology and peripartum labor. This central anticholinergic syndrome is likely caused by blockade of muscarinic cholinergic receptors in the central nervous system. There is no report on Buscopan-induced central anticholinergic syndrome in endoscopy room so far. Three middle-aged females unexpectedly suffered from anterograde amnesia after intramuscular injection of hyoscine butylbromide as an antispasmodic premedication for endoscopy at our endoscopy unit in the Health Promotion Center.It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide （Buscopan; Boehringer Ingelheim, Germany） used as a premedication for endoscopy. However, symptoms or signs associated with the central nervous system are rarely reported in the field of anesthesiology and peripartum labor. This central anticholinergic syndrome is likely caused by blockade of muscarinic cholinergic receptors in the central nervous system. There is no report on Buscopan-induced central anticholinergic syndrome in endoscopy room so far. Three middle-aged females unexpectedly suffered from anterograde amnesia after intramuscular injection of hyoscine butylbromide as an antispasmodic premedication for endoscopy at our endoscopy unit in the Health Promotion Center.

关 键 词：ENDOSCOPY Hyoscine butylbromide Central anticholinergic syndrome AMNESIA 

分 类 号：R595.3[医药卫生—内科学]