疟原虫在蚊体内发育及蚊抗疟原虫感染的分子机制  

Molecular mechanism of Piasmodium development in mosquito and the immune responses of mosquito against Plasmodium

作　　者：王英[1] 黄复生[1] 

机构地区：[1]第三军医大学基础部病原生物学教研室,重庆400038

出　　处：《国际医学寄生虫病杂志》2007年第4期202-207,共6页International JOurnal of Medical Parasitic Diseases

基　　金：国家自然科学基金项目（No.30400363）

摘　　要：疟原虫在蚊体内的发育是个复杂的过程。蚊可在多个环节通过多种机制对入侵的疟原虫产生免疫杀伤作用，以抵抗疟原虫的感染；同时，疟原虫可利用蚊体内发生的一些生物变化逃避蚊的免疫杀伤作用，蚊体内发生的一些生物变化还为疟原虫的发育、繁殖提供了合适的微环境。该文就疟原虫在蚊体内的发育及蚊抗疟原虫感染的分子机制作一综述。Development of Plasmodium in mosquito is a complex journey. Mosquito may kill the invading Plasmodium parasite by a series of mechanisms at multi-points. At the same time, Plasmodium can escape from the immune attack depending on biochanges of mosquito, which also imply an appropriate environment for Plasmodium parasite development and reproduction. This review summarized the molecular mechanism of Plasmodium develoment in mosquito and the immune responses of mosquito against Plasmodium.

关 键 词：蚊 疟原虫 发育 免疫反应 

分 类 号：R384.1[医药卫生—医学寄生虫学]