延黄心痛舒胶囊对麻醉犬心脏血流动力学的影响  

Effects of Yanhang Xintongshu Capsule on Cardiac Hemodynamics in Anesthetized Dogs

作　　者：彭芝配[1] 滕久祥[1] 郜文辉[1] 李为[1] 程玲[1] 

机构地区：[1]湖南中医学院,湖南省长沙市410007

出　　处：《中国全科医学》2007年第16期1330-1332,共3页Chinese General Practice

基　　金：湖南省科技厅重大专项(03SSY1003-S)

摘　　要：目的探讨延黄心痛舒胶囊对麻醉犬心脏血流动力学的影响。方法将健康犬麻醉后,经犬十二指肠给药,用电磁流量计测冠状动脉血流量、心搏出量,用多道生理记录仪测左心室内压。结果给药后,延黄心痛舒胶囊中、高剂量组麻醉犬的冠状动脉血流量、心搏出量、左心室做功与给药前比较差异均有显著性意义(P<0·05)。结论延黄心痛舒胶囊具有改善心脏血流动力学的作用。Objective To investigate the effects of Yanhuang Xintongshu Capsul （YHXTC） on cardiac hemodynamics in anesthetized dogs. Methods After dogs were anaesthetized, drugs of different dose were given from small intestine, And the coronary blood flow （CF） and cardiac output （CO） were measured by electromagnetic flow meter. The internal pressure of left ventricle was determined by carrier amplifier. Results YHXTC significantly inceased CF. CO. the work of left ventricle （ P 〈 0.05）, Conclusion YHXTC can obviously improve cardiac hemodynamics. This study has provided one of the experimental evidence for clinical treatment of ischemic heart disease.

关 键 词：延黄心痛舒胶囊 动物实验 血流动力学现象 

分 类 号：R541[医药卫生—心血管疾病]