基于随机共振检测的神经元非周期激励响应模拟研究  

Simulation for Aperiodic Stimulation Response of Neuron Based on Stochastic Resonance Detecting

作　　者：向学勤[1] 杨翠容[1] 范影乐[1] 李轶[2] 

机构地区：[1]杭州电子科技大学生物医学工程与仪器研究所 [2]浙江大学生物医学工程与仪器学院

出　　处：《电子器件》2007年第4期1436-1439,共4页Chinese Journal of Electron Devices

基　　金：浙江省自然科学基金资助项目(602127)

摘　　要：非周期激励响应对于神经系统的研究具有重要理论意义和应用价值.为了模拟生物感觉系统中检测信号的机制,基于随机共振检测原理,采用互信息率评价方法,对Hodgkin-Huxley单神经元非周期激励响应进行了研究.实验结果表明,Hodgkin-Huxley单神经元不但阈值下存在非周期随机共振现象,在某些特定的条件下,阈值上也同样存在看非周期随机共振现象.由于噪声广泛存在于信号之中,由此,为研究强噪声背景下的神经系统信号检测提供了一种新的方法.As to neural system studies, the response to aperiodic stimulation has shown its important role, both on theory or in practice. By utilizing means of mutual information rate and theory of stochastic resonance detection, in order to simulate ability of organism in signal detection, aperiodic stochastic resonance in single Hodgkin-Huxley neure is studied. Results indicate that, in a single neuron, aperiodic stochastic resonance phenomenon exists not only in subthreshold signal, but in some special situations, aperiodic stochastic resonance for suprathreshold signal is also observed. Thus, this study gives a new method about neural signal detection that under strong noise background, given that real-world signals are typically accompanied with noises.

关 键 词：非周期随机共振 Hodgkin-Huxley神经元 互信息率 阈值上随机共振 

分 类 号：Q811[生物学—生物工程]