正常血压、高血压前期和高血压对冠状动脉微血管功能的影响  

Effects of normal blood pressure, prehypertension, and hypertension on coronary microvascular function

作　　者：Erdogan D. Yildirim I. Ciftci O. 徐永城 

机构地区：[1]Baskent University, Konya Teaching and Medical Research Center, Cardiology Department, Hoca Cihan Mah, Saray Cad, No. 1, Selcuklu, Konya, Turkey Dr.

出　　处：《世界核心医学期刊文摘（心脏病学分册）》2007年第7期35-36,共2页

摘　　要：背景：利用经胸多普勒超声心动图行冠状动脉血流储备（CFR）评估已被用于临床，CFR降低被认为是高血压终末器官受损的灵敏指标；然而，迄今该方法尚未被用于评估高血压前期受试者的CFR。因此，本研究旨在评估高血压前期受试者的CFR。方法和结果：通过经胸多普勒超声心动图检测40例高血压前期受试者、60例高血压患者和50例血压正常健康志愿者的CFR。所有受试者均无系统性疾病。3组受试者之间年龄、性别、体重指数、心率、血脂、空腹血糖和血红蛋白水平均相似。BACKGROUND - The assessment of coronary flow reserve （CFR） by transthoracic Doppler echocardiography has recently been introduced into CFR has been suggested to clinical practice, and reduced be a sensitive indicator of hypertensive endorgan damage; however, to date, this methodology has not been used t0 evaluate CFR in subjects with prehypertension. Accordingly, the present study was designed to evaluate CFR in subjects with prehypertension. METHODS AND RESULTS - We measured CFR of 40 subjects with prehypertension, 60 patients with hyperten- sion, and 50 normotensive healthy volunteers using transthoracic Doppler echocardiography. None of the sub- jects had any systemic disease. Age, gender, body mass index, heart rate, lipid profiles, fasting glucose levels, and hemoglobin were similar among the 3 groups.

关 键 词：高血压前期 冠状动脉微血管功能 经胸多普勒超声心动图 正常血压 冠状动脉血流储备 超声心动图检测 血红蛋白水平 受试者 

分 类 号：R544.1[医药卫生—心血管疾病]