羧甲基壳聚糖的性能及其在生物医学领域的应用  

The Performances and Applications in Biomedicine of Carboxythmethylchitosan

作　　者：赵丽瑞[1] 孙多先[1] 刘满英[2] 

机构地区：[1]天津大学化工学院,天津300072 [2]河北医科大学基础医学院,石家庄050017

出　　处：《高分子通报》2007年第8期43-47,共5页Polymer Bulletin

基　　金：河北省卫生厅资助项目(02055)

摘　　要：羧甲基壳聚糖是一种具有多功能基的天然生物材料,在食品、化妆品、环保、印染、农业等领均有广泛应用。其优良的性能,低廉的价格,使得它在生物医学领域有巨大的的应用潜力。本文综述了羧甲基壳聚糖的水溶性、成膜性、降解性、抗菌性及生物学特性,并对其在烧伤敷料、抗术后粘连材料、药物载体、酶抑制剂等生物医学领域应用的研究进展进行了综述,并指出今后可能的重点研究方向。Carboxymethylchitosan is a kind of nature biomaterial with multi functional groups. It is widely used in food, cosmetic, enviroment protection, printing and dyeing, and agriculture. Becourse of its good performances and low cost it has great potential uses in biomedicine. In this paper we summarized the water solubility, membrane fomation, antimicrobial ability, degradability and biology properties of carboxymethylchitosan and the applications in biomedicine of carboxymethylchitosan including wound dressing, reduction of postoperative adhesions, drug delivery cartier were reviewd generally.

关 键 词：壳聚糖 羧甲基壳聚糖 生物医学材料毛细管电泳 蛋白质分离 吸附 聚合物涂层 

分 类 号：TQ460.4[化学工程—制药化工]