八苄基蔗糖及其水解反应产物的制备  

Study on the preparation and hydrolyzation of octa-O-benzyl sucrose

作　　者：焦岩[1] 方志杰[1] 江荣英[1] 

机构地区：[1]南京理工大学化工学院,江苏南京210094

出　　处：《化学试剂》2007年第8期503-504,506,共3页Chemical Reagents

摘　　要：研究了八苄基蔗糖制备的新方法及其水解反应。通过对蔗糖乙酰化保护得到八乙酸蔗糖酯,再经BnCl、KOH反应得到八苄基保护的蔗糖,总收率81%。八苄基蔗糖在乙酸和硫酸溶液中水解得到2,3,4,6-四-O-苄基葡萄糖和1,3,4,6-四-O-苄基果糖,收率分别为29%和25%。产物结构经1HNMR确证。A new route for preparation and hydrolyzation of octa- O-benzyl sucrose was described in this paper. Firsdy, sucrose oetaacetate was prepared via aeetylation of sucrose, then, oeta-O- benzyl sucrose was obtained from benzylation of sucrose octaacetate using BnCl and KOH as the reagents, resulting in a product yield of 81% after two steps of reactions. Finally, 2,3,4,6- tetra-O-benzyl glucopyranose and 1,3,4,6-tetra- O-benzyl fructofuranose were obtained by hydrolyzation of octa-O-benzyl sucrose in aqueous AcOH and sulfuric acid to achieve a yield of 29% and 21%, respectively. The structure of products was confirmed by 1^HNMR. This process has promising prospects for application.

关 键 词：蔗糖 八乙酸蔗糖酯 八苄基蔗糖 四苄基葡萄糖 四苄基果糖 

分 类 号：O629.1[理学—有机化学]