5-取代色胺盐酸盐的微波合成  

Convenient synthesis of 5-substituted tryptamine by microwave

作　　者：阮秀琴[1] 刘飞[1] 尤启冬[1] 

机构地区：[1]中国药科大学药物化学教研室,江苏南京210009

出　　处：《化学试剂》2007年第8期505-506,共2页Chemical Reagents

摘　　要：Fisher吲哚环合法制备5-取代色胺需在加热条件下进行,传统的加热方式反应时间较长,效率不高。选用分子筛为酸催化剂和助滤剂,利用微波辅助合成色胺,可缩短反应时间,提高反应收率,简化后处理操作,减少对环境的污染。The traditional heating method needs a longer reaction time with low efficiency during the synthesis of 5-substituted tryptamine. Therefore the microwave heating method is utilized to synthesize tryptamine in this context. The zeolite used as the acid catalyst is a green synthetic method and can reduce the pollutants discharged during the reaction.

关 键 词：色胺 微波合成 分子筛 

分 类 号：O625.63[理学—有机化学]