323例药物不良反应报告分析  

Analysis of 323 cases of adverse drug reactions reports

作　　者：恽芸蕾[1] 缪海均[1] 樊成辉[1] 陈万生[1] 

机构地区：[1]第二军医大学长征医院药学部,上海200003

出　　处：《药学实践杂志》2007年第4期261-262,共2页Journal of Pharmaceutical Practice

摘　　要：目的:通过对我院2005年323例药物不良反应(ADR)报表进行统计分析,研究ADR的发生率与患者年龄及用药情况的关系。方法:采用描述性研究方法对ADR报表进行分类。结果:涉及ADR的药物共有194个品种,其中抗感染类药物引起的ADR发生率最高,抗肿瘤药次之。而ADR引发的组织器官损伤最常见于皮肤过敏反应及消化系统症状。结论:应重视安全合理用药,最大限度地减少ADR的重复发生。Objective： To investigate 323 reports of adverse drug reactions （ADRs） in our hospital in 2005 , and to analyze the relationship between ADRs and age , the used drugs. Methods： The cases of ADR were analyzed by descriptive study. Results： 194 kinds of drugs were involved in. Among them, 49 （25.30%） kinds were antibiotis in the first rank, 40 （20.60%） kinds were antineoplastic agents in second rank. ADR showed the lesion of skin and digestive system mostly. Conclusion ： Great attention should be paid to the development of ADR so as to reduce the incidence of ADR.

关 键 词：药物不良反应 药物不良反应监测 统计分析 

分 类 号：R969.3[医药卫生—药理学]