氚标记纤溶酶的制备及其在小鼠体内分布  

The preparation of 3,6-lumbrokinase labelled with tritium and its distribution in mice

作　　者：吴元芳[1] 周桢堂[1] 张雨龙[1] 贺战军[1] 庄道玲[1] 徐葆裕[2,3] 李湘端 杜珍香 蒋方建 邢菁 

机构地区：[1]中国科学院上海原子核研究所 [2]复旦大学 [3]上海医科大学 [4]宁波南海酶工程有限公司

出　　处：《核技术》1997年第5期317-319,共3页Nuclear Techniques

摘　　要：用紫外光激活氚原子法标记三六纤溶酶，并研究它在小鼠体内的分布。实验结果显示，小鼠口服氚标记三六纤溶酶后４８ｈ内，体内各器官中均有不同活度的放射性分布，其达到高峰的时间为４—６ｈ。On the basis of the Chinese traditional medicine 3,6-lumbrokinase powder, a natural enzyme, was separated and purified from the special earthworm with modern biochemical technique. In this paper, 3,6-lumbrokinase powder was labelled with tritium and its absorption and distribution in mice were investigated at different times after oral administration.

关 键 词：三六纤溶酶 氚标记 组织分布 同位素标记 

分 类 号：R817[医药卫生—影像医学与核医学]