老年糖尿病血清载脂蛋白A_1、载脂蛋白B测定分析  

Analysis on the detcrmination of Apolipoprotein (Apo) Al and ApoB within the serum of elderly patients with diabetes mellitus

作　　者：刘永煌[1] 李贵芳[1] 郭丛兰[1] 朱一帆[1] 邹良敏 项筱敏[1] 徐彦英[1] 

机构地区：[1]贵州省人民医院

出　　处：《贵州医药》1997年第1期8-10,共3页Guizhou Medical Journal

摘　　要：为探讨载脂蛋白A1（APOA1）、载脂蛋白B（APOB）与老年糖尿病关系及临床意义．测定54例老年糖尿病载脂蛋白APOA1、APOB．APOA1／APOB，总胆固醇（TC）．甘油三酯（TG）水平。结果：老年糖尿病及心脑并发症组与对照组比较．APOA1及APOA1／APOB无显著差异（p＞0．05）．而APOB．TC．TG显著升高（p＜0．05或P＜0.01）；老年糖尿病并心脑并发症组与单纯糖尿病组比较，APOA1，APOB.TC·TG·APOA1／APOB均无显著差异（p＞0．05）。提示．老年糖尿病存在广泛性脂代谢紊乱。Apolipoprotein (Apo ) A1 , ApoB. cholesterol (TC ) andTriglyceride (TG) levels within serum were determined in 54elderly patients with diabetes mellitus The results show therewas no significant difference among the elderly patients withdiabetes mellitus (mellitus group), the elderly patients withdiabetes mellitus complicated by heart-brain disease (compli-cation group) and the control group in Apo A1 level and thetatio of ApoA1 to ApoB(P > 0. 05). However the ApoB, TCand TG levels in the mellitus group and the complicationgroup were significantly higher than those in the control group(P <0. 05 or P <0. 01) In the comparison of the mellitusgroup and the coniplication group. There were no significantdifference between the two groups in the levels of ApoB,ApoA1/ApoB, TC and TG (P > 0. 05). All these findingsshowed that there were extensive disorders of liptdmetabolism except ApoA1 in elderly patients with diabetesmellitus.

关 键 词：糖尿病 老年人 载脂蛋白A1 载脂蛋白B 

分 类 号：R587.104[医药卫生—内分泌] R592[医药卫生—内科学]