活动性肝炎肝硬化349例临床特点  

Clinical characteristic in 349 patients with active hepatitis cirrhosis

作　　者：吕晓峰[1] 

机构地区：[1]河北省邢台市人民医院肝病科,河北邢台054031

出　　处：《中国现代医学杂志》2007年第15期1908-1909,1914,共3页China Journal of Modern Medicine

摘　　要：目的研究活动性肝炎肝硬化患者的临床特点。方法该科收治的活动性肝炎肝硬化患者349例,分析其年龄、性别与发病的关系,研究不同性别及老年、非老年患者常见并发症、合并症的差异。结果349例活动性肝炎肝硬化男性高发年龄为40～60岁,占男性患者的70.5%,女性高发年龄为50～70岁,占女性患者的71.6%;50岁以上女性患者构成比明显高于男性(80.3%:60.8%,P<0.01);并发原发性肝癌与合并酒精性肝病者男性多于女性(分别为12.6%、4.2%,P<0.05);老年活动性肝炎肝硬化患者构成比女性高于男性(分别为24.0%、14.2%,P<0.05);合并酒精性肝病者老年低于非老年患者(分别为4.2%、12.3%,P<0.05);合并心脑血管病、2型糖尿病和重叠其他肝炎病毒感染者老年明显多于非老年(分别为13.5%、1.2%,P<0.001;18.8%、7.9%,P<0.01;18.8%、5.1%,P<0.001)。结论活动性肝炎肝硬化患者的高发年龄、原发性肝细胞癌和酒精性肝病的发生率有明显的性别差异,老年活动性肝炎肝硬化合并心脑血管疾病、2型糖尿病和重叠感染的发病率与非老年相比显著不同。[Objective] To study the clinical characteristics of the patients with active hepatitis cirrhosis. [Method] 349 patients in our department with active hepatitis cirrhosis were collected and the relationship between their age, sex and the disease was analyzed. We studied the difference of the common complications in male and female, the senior and the other patients. [Result] The age of the male patient with high risk of getting this disease in 349 patients was 40～60, covering 70.5% of the male patients, the age of female was 50～70, covering 71.6% of the female patients; the rate of the female patients of over 50 years old was much higher than the male patients （80.3%： 60.8%, P 〈13.01）; There were more male patients with complication of primary liver cancer and alcoholic liver disease than female patients （relatively 12.6%, 4.2%, P 〈0.05）. The rate of senior female patients with active hepatitis cirrhosis was higher than the senior male patients （relatively 24.0%, 14.2%, P 〈0.05）; There were less senior patients accompanied with alcoholic liver than the others（relatively 4.2%, 12.3%, P 〈0.05）; There were more senior patients accompanied with cerebral cardiovascular disease, Ⅱ diabetes and superinfection than the others （relatively 13.5%, 1.2%, P 〈0.001; 18.8%, 7.9%, P 〈0.01; 18.8%, 5.1%, P 〈0.001）. [Conclusion]There is apparent difference between the incidence of primary liver cancer, alcoholic liver disease and the age of patients with high risk of getting active hepatitis cirrhosis, the incidence of senior patients with active hepatitis cirrhosis accompanied with cerebral cardiovascular disease, Ⅱ diabetes and superinfection is apparently different from that of others.

关 键 词：活动性肝炎肝硬化 并发症 性别 年龄 发病率 

分 类 号：R512.6[医药卫生—内科学]