亚低温治疗弥漫性轴索损伤69例临床观察  

The therapeutic effect of sub-hypothermia on diffuse axonal injury (report of 69 cases)

作　　者：李子坚[1] 林言华[1] 容耔耘[1] 仇尔宁[1] 

机构地区：[1]佛山市顺德区第一人民医院神经外科,广东佛山528300

出　　处：《临床和实验医学杂志》2007年第9期41-42,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨亚低温治疗弥漫性轴索损伤(DAI)的临床疗效。方法将139例DAI患者随机分为亚低温组69例,常温组70例,比较两组治疗前后的脑组织氧分压、颅内压、血气分析、重要脏器功能指标及预后。结果与对照组比较,治疗组亚低温治疗能显著提高患者脑组织氧分压(P<0.01)、提高恢复良好率(P<0.01),明显降低颅内压(P<0.01)和死亡率(P<0.05)。结论弥漫性轴索损伤早期辅助亚低温下综合治疗,可降低病死率和提高恢复良好率。Objective To investigate the therapeutic effects of sub - hypothermia on diffuse axonal injury （DAI）. Methods 139 patients with DAI were ramdomly assigned to receive sub - hypothermie or normothermic treatment. Results Compared with normothermic treatment, sub - hypothermic treatment was associated with significantly elevated brain tissure oxygen tension （ P 〈0.01 ） , higher recovery rate （ P 〈0.01 ） , reduced intracranial pressure （ P 〈 0.01 ） and mortality. Conclusion Sub - hypothermic treatment can improve patients＇ prognosis, lower mortality ; it is a safe and effective treatment for diffuse axonal injury, deserve recommendation.

关 键 词：弥漫性轴索损伤 亚低温治疗 预后 

分 类 号：R651.15[医药卫生—外科学]