氧化钛薄膜的血液相容性研究  

BLOOD COMPATIBILITY OF TITANIUM OXIDE FILMS SYNTHESIZED BY ION BEAM ENHANCED DEPOSITION

作　　者：张峰[1,2,3,4,5] 黄楠[1,2,3,4,5] 郑志宏[1,2,3,4,5] 杨萍 曾小兰 毛应俊[1,2,3,4,5] 刘芳艳 陈安清[1,2,3,4,5] 周美英 朱德彰 蒋振斌[1,2,3,4,5] 王中尧 柳襄怀[1,2,3,4,5] 

机构地区：[1]中科院上海冶金研究所离子束开放研究实验室 [2]西南交通大学材料系 [3]中科院上海原子核研究所 [4]上海市心血管病研究所 [5]上海医疗器械研究所

出　　处：《功能材料与器件学报》1997年第1期47-54,共8页Journal of Functional Materials and Devices

基　　金：国家自然科学基金;上海市自然科学基金

摘　　要：本文研究了离子束增强沉积技术制备的氧化钛薄膜的血液相容性与薄膜的结构、成分、表面能，以及蛋白质在薄膜表面的吸附之间的关系。实验表明，血液相容性是表面能和功函数共同作用的结果。表面能决定蛋白质的吸附量，功函数决定蛋白质的变性。on beam enhanced deposition was used to synthesize titanium oxide film. The blood compatibility of the film and its relation to structure, composition, surface energy and protein adsorption were studied. The results indicate that the blood compatibility is related to the surface energy and work function of titanium oxide film. The amount of adsorbed protein is determined by surface energy and the denaturation of adsorbed protein depends on work function of the film. The mechanism of blood compatibility was discussed.

关 键 词：人工心脏 瓣膜材料 氧化钛 薄膜 血液相容性 

分 类 号：R318.11[医药卫生—生物医学工程] R318.08[医药卫生—基础医学]