广西某市学龄前儿童血铅水平及其与微量元素的关系  

Correlation Analysis on Levels of Lead and Trace Elements in Blood among Preschool Children in a City of Guangxi

作　　者：陈红慧[1] 傅雪[2] 姜岳明[2] 江蕙芸[1] 谢佩琳[1] 王小莲[1] 黄一星[1] 

机构地区：[1]广西壮族自治区人民医院,广西南宁530021 [2]广西医科大学,广西南宁530021

出　　处：《工业卫生与职业病》2007年第4期226-228,共3页Industrial Health and Occupational Diseases

基　　金：广西科学研究与技术开发计划项目(桂科攻0632007-3F)

摘　　要：目的　探讨广西某市学龄前儿童血铅（Pb）水平及其与锌（Zn）、铜（Cu）、铁（Fe）、钙（Ca）、镁（Mg）、锰（Mn）含量的关系。方法　对624名2-5岁学龄前儿童测定血Pb、Zn、Cu、Fe、Ca、Mg、Mn含量,并对血Pb与Zn、Cu、Fe、Ca、Mg、Mn等含量进行相关性分析。结果　以美国国家疾病控制中心（CDC）制定的铅中毒标准（血Pb水平≥100μg/L）为界线,学龄前儿童的铅中毒检出率为22.6%,其中男童及其4岁-组铅中毒检出率明显高于女童及其对应亚组;男童血Pb和Cu含量高于女童（P〈0.05,P〈0.01）。但是,血Pb水平与6种微量元素含量之间未见明显相关关系。结论　多元线性回归分析未见学龄前儿童血Pb与Zn,Fe,Cu,Ca,Mg,Mn含量之间有相关关系。Objective To explore the correlation between blood lead level and blood levels of six trace elements, i.e. zinc （Zn）, copper （Cu）, iron （Fe）, calcium （Ca）, magnesium （Mg）, and manganese （Mn） among preschool children in a city of Guangxi. Methods Blood samples of 624 preschool children of 2 -5 years old were collected to determine the blood lead level and blood levels of six trace elements. Moreover, a correlation analysis on levels of blood lead and blood Zn, Cu, Fe, Ca, Mg and Mn was made. Results According to criteria of lead poisoning （blood lead level greater than or equal to 100μg/L） formulated by Center for Disease Control of the US, the incidence rate of lead poisoning of preschool children was 22.6%. Furthermore, the incidence rates of lead poisoning of boys in total groups and 4-year-old group （P〈0.05, P〈0.01）, their blood lead level （P〈0.05） and blood Cu concentration （P〈0.05） were significantly higher than those of girls. Results showed that there was little correlation between blood level of lead and blood levels of Zn, Fe, Cu, Ca, Mg and Mn. Conclusions There was no correlation between blood level of lead and blood levels of Zn, Fe, Cu, Ca, Mg and Mn among preschool children in this study.

关 键 词：学龄前儿童 血铅水平 微量元素 

分 类 号：R446.11[医药卫生—诊断学]