孕大鼠和胎鼠心脏系统混沌特征分析  

Chaotic Analysis on Cardiac Systems of Normal Pregnant Rats and Fetuses

作　　者：邵勇[1] 姚珍薇[1] 陆杰[2] 罗红霞[3] 吴味辛[1] 丁敏[4] 

机构地区：[1]重庆医科大学附属第一医院妇产科,重庆400016 [2]重庆医科大学生理教研室,重庆400041 [3]重庆医科大学附属第一医院卫生学校,重庆400016 [4]重庆医科大学医学检验系,重庆400041

出　　处：《生物医学工程学杂志》2007年第4期902-905,共4页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(20475069)

摘　　要：应用计算机化大鼠心电信号采集和处理系统,引导妊娠第21dSD大鼠和胚胎宫内心电,记录母胎鼠心动周期信号混沌图形参数和数值参数,探讨正常妊娠大鼠母胎心脏系统混沌特征,分析母胎鼠自主神经系统发育的差异性。结果显示,(1)正常胎鼠与孕鼠比较,频率和电压较低,差异均有显著性(P<0.01);(2)正常胎鼠和孕鼠心动周期信号功率谱具有类似于人的心动周期信号功率谱三峰特征;正常胎鼠和孕鼠比较,第二峰、第三峰明显较低;(3)正常胎鼠与孕鼠比较,相对分散度、李雅普诺夫指数和分维数均显著较低,差异均有显著性(P<0.01)。本研究表明,正常胎鼠心动周期信号变化的复杂性低于孕鼠,胎鼠心脏混沌程度低于孕鼠,胎鼠自主神经系统发育尚不成熟。This investigation was made to explore the chaotic characteristics of cardiac system and differences of autonomic nervous system development of normal pregnant rats and fetuses. The electrocardiograms, chaotic graphics and digital characteristics of heart period signal （HPS） of normal pregnant rats and fetuses by day 21＇＇ were evaluated with a computerized HPS extracting and analyzing system. Results ：（1）The mean values of frequency and voltage of fetal rats electrocardiograms were lower than those of pregnant rats significantly （P〈0.01）. （2）Being similar to those in human, the chaotic graphics showed three-amplitudes spectral features in both normal pregnant rats and fetuses. However, the second amplitude and third amplitude were lower in fetal rats than in pregnant rats. （3）The Heart Relative Dispersion, Lyapunov Exponent and Fractional Dimension were significantly lower in fetal rats than in pregnant rats （P〈 0. 01）. These findings demonstrated that the autonomic nervous system development of fetal rat was still immature and it exhibited lower complexity of HPS and chaotic degree than that of pregnant rat did.

关 键 词：正常妊娠 胎鼠 心动周期信号 混沌分析 自主神经系统 

分 类 号：R714[医药卫生—妇产科学]