清开颗粒灌肠治疗肝硬化合并肝性脑病疗效观察  

Clinical Observation of "Qingkai Granule" in Treating Cirrhotic Patients with Hepatic Encephalopathy

作　　者：卓蕴慧[1] 商斌仪[1] 陈建杰[1] 徐玉萍[1] 张颖[1] 姚军[1] 王燕[1] 

机构地区：[1]上海中医药大学附属曙光医院肝炎科,上海201203

出　　处：《上海中医药杂志》2007年第8期27-28,共2页Shanghai Journal of Traditional Chinese Medicine

基　　金："十五"国家攻关资助项目(2001BA701A21)

摘　　要：目的观察清开颗粒治疗肝硬化合并肝性脑病的疗效。方法肝硬化合并肝性脑病62例,随机分成治疗组和对照组。两组西医常规治疗相同,治疗组(n=32)用清开颗粒联合常规疗法治疗,对照组(n=30)用乳果糖联合常规疗法治疗。两组均治疗7d。结果治疗组清醒时间平均为(19.6±11.8)h,对照组为(26.9±13.2)h(P<0.05);治疗组显效率和总有效率分别为34.3%和87.5%,对照组为23.3%和73.3%,治疗组疗效优于对照组,差异有显著性意义(P<0.05);治疗组NCT、DS、血氨的改善程度与对照组比较有显著性差异(P<0.05)。结论清开颗粒治疗肝性脑病能提高临床疗效。Objective To observe the efficacy of ＂Qingkai Granule＂ in treating cirrhotic patients with hepatic encephalopathy. Methods Sixty- two cirrhotic patients with hepatic encephalopathy were randomly divided into two groups. Thirty-two patients in treatment group were treated with ＂Qingkai Granule＂ and conventional therapy, and patients in control group were treated with Lactulose combined with conventional therapy. Results There was a significant difference in the excellent effective rate and the total effective rate between the two groups （P〈 0.05）. Conclusion ＂Qingkai Granule＂ is effective for hepatic encephalopathy.

关 键 词：肝硬化 肝性脑病 清开颗粒 灌肠 数字连接试验 数字符号试验 

分 类 号：R259[医药卫生—中西医结合]