浅裂鳞毛蕨根茎中的二氢黄酮苷类化学成分(英文)  

Flavanone O-glycosides from the rhizomes of Dryopteris sublaeta

作　　者：冯卫生[1] 曹新伟[1] 匡海学[2] 郑晓珂[1] 

机构地区：[1]河南中医学院,河南郑州450008 [2]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《药学学报》2007年第8期867-871,共5页Acta Pharmaceutica Sinica

基　　金：Project supported by the Key Project of Chinese Ministry of Education(2003078).

摘　　要：为研究浅裂鳞毛蕨根茎中的化学成分,用Sephadex LH-20,silica gel等柱色谱方法从其水提物中分离得到化合物,并根据理化性质和波谱数据鉴定其结构.分离得到9个化合物,分别为浅裂鳞毛蕨素A（1）,浅裂鳞毛蕨素B（2）,浅裂鳞毛蕨素C（3）,浅裂鳞毛蕨素D（4）,东方荚果蕨酯A（5）,东方荚果蕨酯C（6）,熊果苷（7）,3-甲氧基-4-羟基苯基-1-O-β-D-葡糖苷（8）和3,4-二甲基苯基-1-O-β-D-葡糖苷（9）.其中化合物1～4为新化合物,其余均为首次从本植物中分得.The aim of this study was to look for the chemical constituents from the rhizomes of Dryopteris sublaeta. The fresh plant was extracted twice with boiling water, the extract was concentrated to small volume under reduced pressure at 50 ℃. The concentrated material was partitioned with ether, ethyl acetate and n-butanol. The fraction of ethyl acetate was repeatedly chromatographied over silica gel and Sephadex LH-20 columns. Structures of pure compounds were established on the basis of their physiochemical and spectral data. Nine compounds were obtained and identified as sublaetentin A （1）, sublaetentin B （2）, sublaetentin C （3）, sublaetentin D （4）, matteuorienate A （5）, matteuorienate C （6）, arbutin （7）, 3-methoxy-4-hydroxyphenyl-1-O-β-D-glucopyranoside （8） and 3,4-dimethoxyphenyl-1-O-β-D-glucopyranoside （9）. Compounds 1-4 are new compounds, the others were isolated from this plant for the first time.

关 键 词：浅裂鳞毛蕨 二氢黄酮苷 结构鉴定 

分 类 号：R284.1[医药卫生—中药学]