流动注射-化学发光法测定盐酸地尔硫卓  

Investigation on the post chemiluminescence behavior of diltiazem hydrochloride

作　　者：高申霞[1] 吕九如[1] 

机构地区：[1]陕西师范大学化学与材料科学学院,西安710062

出　　处：《分析试验室》2007年第4期21-24,共4页Chinese Journal of Analysis Laboratory

摘　　要：发现了盐酸地尔硫卓在过硫酸钾-鲁米诺化学发光反应体系中的后化学发光反应。据此发现建立了利用后化学发光反应测定盐酸地尔硫卓的流动注射化学发光新方法。方法的线性范围为3.0×10-6～1.0×10-4g/mL,检出限为3×10-7g/mL,对6.0×10-5g/mL的盐酸地尔硫卓标准溶液进行11次平行测定的相对标准偏差为1.6%。方法已用于盐酸地尔硫卓片剂中盐酸地尔硫卓含量的测定。　In this work,a new post-chemiluminescence （PCL） reaction was found when diltiazem hydrochloride was injected into the potassium persulfate-luminol system.Using the PCL,a method for the determination of diltiazem hydrochloride was established.The linear response range of this method was from 3.0×10^-6 to 1.0×10^-4 g/mL with a linear correlation coefficient of 0.9966.The relative standard deviation for 3.0×10^-7 g/mL diltiazem hydrochloride solution was 1.6%（n=11）.This method had been successfully applied to determine diltiazem hydrochloride in a medicament with a satisfactory result.

关 键 词：后化学发光 过硫酸钾 鲁米诺 盐酸地尔硫卓 

分 类 号：O657.3[理学—分析化学]