女性小儿单纯性肥胖症患者血清leptin和E_2检测的临床意义  

Clinical Significance of Determination of Changes of Serum Leptin and E_2 Levels in Females Children with Simple Obesity

作　　者：白华[1] 钱明珠[1] 

机构地区：[1]江苏省连云港市第一人民医院儿内科,222002

出　　处：《放射免疫学杂志》2007年第4期306-307,共2页Journal of Radioimmanology

摘　　要：目的:探讨了小儿单纯性肥胖症患者血清瘦素(leptin)和E2水平的变化及意义。方法:应用放射免疫分析对32例女性小儿单纯性肥胖症患者进行了血清leptin和E2的检测,并以35名正常健康女童为对照。结果:女性单纯性肥胖症患儿血清leptin和E2水平非常显著地高于正常女童组(P<0.01),且两者呈明显的正相关(r=0.6013,P<0.01)。结论:检测女性小儿单纯性肥胖症患儿血清leptin和E2水平的变化对了解病情、指导临床实践均具有一定的临床实用价值。Objective To investigate the clinical significance of changes of serum leptin and E2 levels in females children with simple obesity. Methods Serum levels of leptin and E2 were detected with RIA in 32 females children with simple obesity and 35 controls. Results In the children with simple obesity the serum leptin and Fa levels were significantly higjer than those in controls （ P 〈 0.01 ） and were mutully positively correlated. Conclusion Determination of serum leptin and E2 levels is of help for judgement of severity of obesity as well as outcome prediction in female children.

关 键 词：女性小儿单纯性肥胖症 瘦素 雌二醇 

分 类 号：R725.81[医药卫生—儿科]