血浆BNP测定在老年性呼吸困难鉴别诊断中的应用  

Differential Diagnostic Value of Plasma BNP Concentration Determination in Elderly Patients with Dyspnea

作　　者：王克俊[1] 荆蕊平[1] 任更朴[1] 齐子芳[1] 刘俊茹[1] 

机构地区：[1]山东省聊城市第二人民医院,252601

出　　处：《放射免疫学杂志》2007年第4期366-367,共2页Journal of Radioimmanology

摘　　要：目的:探讨血浆BNP水平在老年性呼吸困难鉴别诊断中的应用。方法:选择呼吸困难的老年患者共96例,选择对照组46例,用荧光免疫法快速测定BNP水平。结果:对明确诊断的心源性呼吸困难患者43例和肺源性呼吸困难患者53例,进行回顾性分析,其血浆BNP水平分别为(841.32±431.22)pg/ml和(158.43±96.26)pg/ml;对照组46例,其血浆BNP水平为(51.26±19.16)pg/ml。心源性呼吸困难患者与对照组及肺源性呼吸困难患者比较,其血浆BNP水平均有非常显著差异(P<0.01)。结论:血浆BNP水平测定对老年性呼吸困难的快速鉴别诊断具有较重要的意义。Objective To study the differential diagnostic value of plasma BNP concentration determination in elderly patients with dyspnea. Methods Plasma BNP levels were measured with fluorescence immunoassay in 96 elderly patients with dyspnea and 46 controls. Results The plasma levels of BNP in patients with dyspnea from congestive heart failure （ 841.32 ± 431.22） pg/ml were significantly higher than those in patients with dyspnea from primary pulmonary origin （ 158.43 ±96.26） pg/ml and controls （51.26 ± 19.16） pg/ml （both P 〈 0.01 ）. Conclusion The rapid assay of plasma BNP concentration is useful in differentiatial diagnosis in elderly patients with dyspnea （heart failure vs pulmonary disease）.

关 键 词：B型钠尿肽 老年性患者 呼吸困难 鉴别诊断 

分 类 号：R473.5[医药卫生—护理学]