性病高危人群HPV DNA分型检测结果分析  

Analysis of Human Papillomavirus DNA Genotyping in High Risk Sexually Transmitted Diseases Group

作　　者：金宁[1] 刘文力[1] 杨琳[1] 梁金珠[1] 韩莹[1] 

机构地区：[1]沈阳市第七人民医院皮肤科,辽宁沈阳110003

出　　处：《中国皮肤性病学杂志》2007年第8期490-491,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的分析性病高危人群HPV-DNA分型检测的结果。方法采用荧光定量聚合酶链反应技术(FQPCR)对541例性病高危人群进行HPV-DNA分型检测。结果男、女HPV阳性率分别为38.69%和52.63%,141例疣体中HPV阳性率为73.76%,其中男、女疣体HPV阳性率分别为61.54%和80.90%,400例分泌物中HPV阳性率为38.25%,其中男、女分泌物HPV阳性率分别为30.61%和42.69%,两者差异均具有显著性。配偶患CA者、CA治疗后复查者和自检者的HPV阳性率分别为44.12%,45.88%和33.33%。结论性病高危人群HPV检出率均较高,且女性高于男性。配偶患CA者、CA治疗后者和自检者也存在较高的HPV感染,应重视对这些人群的HPV常规检测。Objective To analyse the results of human papillomavirus（HPV） DNA genotyping in high risk sexually transmitted diseases group. Methods Five hundred forty one samples coming from outpatients in high risk sexually transmitted diseases group were examined by fluorescent quantitative polymerase chain reaction （FQ-PCR） to genotype human papilomavirus DNA. Resuits The HPV positive rates of male and female outpatients were 38.69% and 52.63%, respectively. The HPV positive rate of 141 condylomas was 73.76%. The positive rates of male and female groups were 61.54% and 80.90% , respectively. The HPV positive rate of 400 secretions was 38.25%. The positive rates of male and female groups were 30.61% and 42.69% , respectively. The difference of both groups had statistical significance. The HPV positive rate of sexual spouse suffered from CA, patients with CA treated and patients who asked to examine selves were 44.12% ,45.88% and 33.33% ,respectively. Conclusion High risk STD group may be detected high HPV positive rate and female higher than that of male. The HPV positive rate of sexual spouse suffered from CA, patients with CA treated and patients who ask to examine selves were higher. It should be paid more attention to detect HPV regularly for high risk STD group.

关 键 词：尖锐湿疣 人乳头瘤病毒 荧光定量聚合酶链反应 

分 类 号：R759[医药卫生—皮肤病学与性病学]