应变率显像对左室不同层次心肌舒张早期应变率的研究  

Evaluation of Strain Rate in Different Layers of Left Ventricular Myocardium in Early Diastole Using Strain Rate Imaging

作　　者：吉日[1] 任卫东[1] 李玉峰[1] 晏华[2] 陈昕[1] 郭宝生[1] 周洁莹[1] 

机构地区：[1]中国医科大学附属第一医院心血管检查科,沈阳市110001 [2]沈阳市大众医院

出　　处：《中国超声医学杂志》2007年第8期590-592,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的应用应变率成像评价正常人与高血压患者舒张早期左室不同层次心肌的应变率差异。方法高血压组22例,正常对照组28例,行常规二维超声心动图检查后,采集左室乳头肌短轴二维组织多普勒图像,应用QLab软件中将应变率取样容积分段的方法,脱机分析该切面左室后壁心肌舒张早期心内膜下、心外膜下心肌应变率(SRendo、SRepi)峰值及平均应变率(SRmean)峰值。结果正常人心肌舒张早期存在应变率阶差,心内膜下心肌应变率显著高于心外膜下心肌(P<0.001);与正常组比较,高血压组SRendo、SRmean显著降低,差异有统计学意义(P<0.001),而SRepi无统计学差异(P=0.58)。结论通过将应变率取样容积分层的方法可以检测出不同层次心肌应变率的差别,从而为进一步了解局部心肌的生理运动和病理改变提供了一种简便、无创、准确、重复性较好的研究方法。Objective To evaluate ultrasound-based strain rate in different layers of left ventricular myocardium of normal people and patients with hypertension （HBP） during early diastole. Methods TDI （tissue Doppler imaging）data were obtained from the left mid ventricular short-axis view in 28 healthy people and 22 patients with hypertension using high frame rate imaging. Peak strain rates in the endocardial （SRendo）, epicardial （SRepi） layers were measured simultaneously during early diastolic period at the left ventricular posterior wall using QLab software, with which sampling volume （M-line） of myocardium can be subdivided into three sub-regions equally： endocardium, mid-myocardium and epicardium. Peak mean strain rate of all layers （SRmean） was also evaluated. Results There was strain rate gradient between endocardium and epicardium in normal people in early diastole, that is, SRendo was obviously higher than SRepi （P〈0. 001） . In HBP group, SRendo and SRmean was significantly decreased （P〈0. 001） while SRepi appeared no difference （P= 0.58） compared with those in healthy individuals. Conclusions Strain rate in different myocardium layers can be evaluated using SRI. We present a noninvasive, simple, precise and reproducible method which may be useful for detailed analysis of regional myocardial function.

关 键 词：应变率显像 心内膜下心肌 心外膜下心肌 

分 类 号：R445.1[医药卫生—影像医学与核医学]