HIFU与药物保守治疗宫外孕后输卵管通畅性的对比研究  

A Comparison of Tubal Patency in Treatment of Ectopic Pregnancy:HIFU Therary vs Chemotherapy

作　　者：巩箫音[1] 周晓东[1] 陈定章[1] 韩增辉[1] 于铭[1] 秦海英[1] 孔洁[1] 宋晶[2] 

机构地区：[1]解放军第四军医大学西京医院超声诊断科 [2]中国人民解放军96263部队卫生队

出　　处：《中国超声医学杂志》2007年第8期608-611,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的应用超声晶氧造影观察高强度聚焦超声(HIFU)及药物保守治疗输卵管妊娠后输卵管的通畅性,比较2种治疗方法的预后。方法将我院同期收治的68例输卵管妊娠患者根据治疗方法的不同分为两组,HIFU治疗组33例(A组),药物保守治疗组35例(B组)。治疗后待血HCG值降至正常水平时用1%的晶氧造影剂分别对两组患者行B-flow超声模式监控下的输卵管造影,观察患侧输卵管的通畅性。结果HIFU组患侧输卵管通畅17例(51.52%),通而不畅11例(33.33%),阻塞5例(15.15%);保守治疗组患侧输卵管通畅9例(25.71%),通而不畅12例(34.29%),阻塞14例(40.00%),两组通畅率差异具有显著性意义(P<0.05)。结论超声晶氧造影发现HIFU治疗后输卵管通畅率高于保守治疗。HIFU是一种新的安全、有效的输卵管妊娠治疗方法,不仅能保留患侧输卵管且治疗后输卵管通畅率较高,适用于有生育要求的患者。Objective To compare the tubal patency rate between the high intensity focused ultrasound （HIFU） and chemotherapy in the treatment of ectopic pregnancy by carbamide peroxide hysterosalpingography. Methods A total of 68 patients with ectopic pregnancy were divided into two groups ： Group A （33 cases） was treated with HIFU and group B （35 cases） was treated with chemotherapy. When HCG was decreased to normal level after treatment, 1% carbamide peroxide was injected into the uterine cavity and the blood flow on B-flow imaging was observed and the tubal patency condition was assessed, Results In group A, there were 17 cases （ 51.520% ）who got tubal patency, 11 cases （33.33 % ）got partial patency and 5 cases （ 15.15 % ）were still obstructed, In group B, there were patent tubes in 9cases （25.71%）; partially patent in 12 cases （34.29%） and obstruction was in 14 cases （40.0%）. There were significant differences in the patency rate between the two groups （P〈0.05）. Conclusions Patency rate of ductus Mueller was higher in the HIFU group than those in chemotherapy group, using carbamide peroxide （C BMPO ） for ultrasonic contrast hysterosalpingography, Compared with chemotherapy treatment, HIFU is a prominent therapy in the treatment of ectopic pregnancy with security and convenience.

关 键 词：高强度聚焦超声 输卵管妊娠 保守化学治疗 超声输卵管造影 氨基甲酸过氧化物(晶氧) 

分 类 号：R714.22[医药卫生—妇产科学]