低分子肝素钙对反复自然流产患者ACA的影响及疗效分析  

Effect of low-molecular weight heparin calcium on the patients of anticardiolipin antibody-positive recurrent spontaneous abortion

作　　者：谢家凤 

机构地区：[1]佛山市南海区人民医院,广东佛山528200

出　　处：《山东医药》2007年第19期64-65,共2页Shandong Medical Journal

摘　　要：目的观察低分子肝素钙对反复自然流产患者的治疗疗效及血清抗心磷脂抗体(ACA)水平的影响。方法采用酶联免疫吸附法测定反复自然流产患者血清ACA的水平,将45例ACA阳性患者随机分为两组,治疗组30例应用低分子肝素钙进行治疗,对照组15例仅用泼尼松和阿司匹林口服治疗。结果治疗组ACA转阴率及流产治愈率均达90%(27/30),对照组均为20%(3/15),两组比较有统计学差异。结论低分子肝素钙能抑制反复自然流产患者ACA的产生,有效治疗ACA阳性引起的反复自然流产。[ Objective ] To explore the therapeutical effect of low-molecular weight heparln calcium on the patients of anticardiolipin antibody （ACA） -positive recurrent spontaneous abortion （AARSA）. [ Methods ] The level of ACA was measured by enzyme linked immunoabsorbent assay （ELISA） on the patient s of AARSA. 45 cases were divided into two groups randomly. In treatment group, 30 cases were treated with low-molecular weight heparin calcium. And then the patients were only treated with prednisone and aspirin in control group. [ Results ] After treatment, ACA negative in the treated group was 90.0% （27/30）, and the curative rate of abortion in treated group was 90.0%. While in the control group, ACA negative was 20.0% （3/15）, and the curative rate of abortion was 20.0%. Comparison between the two groups showed significant difference. [ Conclusion] Low-molecular weight heparin calcium can cure AARSA effectively.

关 键 词：低分子肝素钙 反复自然流产 抗心磷脂抗体 

分 类 号：R714.21[医药卫生—妇产科学]