腹腔镜手术联合米非司酮治疗子宫内膜异位症46例临床分析  

Efficacy of the combined laparoscopy and mifepristone in the treatment of 46 pelvic endometriosis

作　　者：黄作香[1] 徐博[1] 

机构地区：[1]三峡大学第三临床医学院妇产科,湖北宜昌443002

出　　处：《中国妇幼保健》2007年第25期3507-3508,共2页Maternal and Child Health Care of China

摘　　要：目的:研究腹腔镜与米非司酮联合治疗子宫内膜异位症的疗效。方法:2004年1月～2005年1月在葛洲坝中心医院就诊的90例子宫内膜异位症患者腹腔镜术后,随机分为两组:单纯腹腔镜手术组44例;联合治疗组46例,术后每天口服米非司酮10mg连续3个月。所有患者随访3～12个月。结果:随访率97.70%(88/90)。单纯手术组有效率41.80%,联合治疗组有效率66.70%,明显高于单纯手术组(P<0.05)。结论:腹腔镜手术后补充小剂量米非司酮可以作为治疗子宫内膜异位症的方案之一。Objective： To investigate the effects of the combined laparescopy and mifepristone for treating for patients with endometriosis. Methods： Ninety patients with endometriosis were divided into two groups randomly in Gezhouba Center Hospital from Jan 2004 to Jan 2005 as single laparoscopic group and combined therapy group, containing 44 and 46 patients, respectively. In the second group, mifepristone was administered in a dose of 10 mg/d continuously for 3 months in each patient. All the patients had been followed up for 3 to 12 months. Results： The follow - up rate was 97. 7% （88/90）. The effective rate of single operation group was 41.8%, while it was 66. 7% in the combined therapy group, which was much higher than that of first group （P 〈 0. 05） . Conclusion： Administering of low dose mifepristone after laparoscopic operation could be a promising avenue of endometriosis treatment.

关 键 词：子宫内膜异位症 米非司酮 腹腔镜 

分 类 号：R711.71[医药卫生—妇产科学]