中国成年男子膳食、器官组织和尿中元素含量研究的辐射防护应用  

Application of the elemental contents in diet, organ or tissues and urine for Chinese adult men in radiation protection

作　　者：诸洪达[1] 王京宇[2] 武权[1] 王耐芬[2] 樊体强[1] 刘虎生[2] 刘庆芬[1] 王小燕[2] 欧阳荔[2] 刘雅琼[2] 解清[2] 

机构地区：[1]中国医学科学院中国协和医科大学放射医学研究所,天津300192 [2]北京大学公共卫生学院

出　　处：《中华放射医学与防护杂志》2007年第4期373-380,共8页Chinese Journal of Radiological Medicine and Protection

基　　金：国家自然科学基金资助项目（30370443,39970234和39570234）

摘　　要：目的将本项目3个阶段所获总结果应用于我国辐射防护领域。方法依据平衡条件下元素与其放射性核素理化和生物学性质同一性，按文献方法讨论了本研究结果在辐射防护领域主要应用。结果除在前3篇文章中讨论了为中国参考人器官、组织及全身元素浓度和负荷量参数参考值及其分布提供依据外，更新了我国元素膳食摄人量，提供了某些放射防护用生物动力学模型重要参数（f1、Te和Tb）参考值的相应依据；估算了我国原生放射性核素所致内剂量和元素由环境向人体关键器官转移系数。结论为确定中国参考人42种元素膳食摄人量、60种元素18种主要器官、组织及全身负荷量和56种元素尿日排出量参数和某些生物动力学模型参数提供了参考值依据，估算了原生放射性核素所致内剂量和元素由环境向人体关键器官转移系数和同体全血与尿样中元素含量关系。Objective To apply the obtained results from 3 stages of research in Chinese radiation protection field. Methods Based on the idemification of physical, chemical and biological qualities for dement and its radionuchdes under equilibrium condition, main apphcation of these results in Chinese radiation protection field have been discussed by using reported methods in hterature. Results Based on developing elemental reference values of organs or tissues, whole body burdens and their distribution for Chinese Reference Man, discussed in the above 3 articles, current dietary elemental intakes of 42 elements have been updated, and related basis for certain important parameters of bio-kinetic model for use in radiation protection （ for example, f1, Te and Tb ） have been provided. The internal doses from primordial radionuclides and transfer coefficients of elements from environment into the critical organts of Chinese adult men have been estimated. Conclusions The series of research have provided basis for developing the reference values of parameters on dietary intakes of 42 dements, burdens of 60 dements in the 18 organs or tissues as well as whole body, daily urinary excretion of 56 elements and some important parameters of bio-kinetic models for Chinese Reference Man. The internal dose from primordial radionuchdes for Chinese adult men, the transfer coefficients of these elements from environment into the critical organts in China and the inter relation between elemental contents in whole blood and urine samples from identical subjects have been estimated.

关 键 词：元素 辐射防护 器官 组织 生物动力学模型参数 转移参数 

分 类 号：R1[医药卫生—公共卫生与预防医学]