纳米粒子-生物分子复合体的合成及其在生物医药领域的应用  

The Synthesis of Integrated Nanoparticle-Biomolecule Hybrid Systems and Applications in the Bio-medical Field

作　　者：徐文涛[1] 陈艳[1] 陈伟[1] 龙德鸿[1] 杨旭石[1] 沈鹤柏[1] 

机构地区：[1]上海师范大学,上海200234

出　　处：《现代生物医学进展》2007年第8期1251-1255,共5页Progress in Modern Biomedicine

基　　金：国家自然科学基金(20443005)

摘　　要：纳米粒子具有独特的光、电和催化性质;生物物质具有识别、催化和抑制的特性;纳米粒子连接生物分子从而合成了具有生物上的电、光性质的纳米粒子—生物分子复合体。本文介绍了纳米粒子-生物分子复合体系的合成,以及这些纳米粒子—生物分子复合体在生物医学领域的应用及研究进展。Nanoparticles exhibit similar dimensions to those of biomolecules, Nanoparticles exhibit unique electronic, photonic and catalytic properties, and biomaterials display unique discriminating, catalytic, and inhibitory properties. The integration of the two forms a novel hybrid material of synergetic properties and functions which called biomolccule-nanoparticle. This review outlines recent advances in synthesis of biomoleculc-nanoparticle hybrid systems, and its application in the generation of 2D and 3D ordered structures in the solution or on the surfaces[0], with emphasis on the use of biomolecule-nanoparticle （metallic or semiconductive） assemblies for bloanalytical applications and for the fabrication of bioelectronic devices.

关 键 词：纳米粒子 生物分子复合体 生物传感器 纳米生物技术 磁性分离 

分 类 号：O611.4[理学—无机化学]